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Researchers from the MRC-Human Immunology Unit, supported by the NIHR Oxford Biomedical Research Centre, have used an ‘atlas’ of immune cells in the human colon to find evidence of the role of CD8 T cells in inflammatory bowel disease. The findings could pave the way for more targeted treatments for this chronic disorder.
CDIN1-Codanin-1 complex defective in congenital dyserythropoietic anaemia type I is an RNA nuclease.
Conference paper
Brolih S. et al, (2026), Nat Commun
CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis.
Journal article
Rampotas A. et al, (2026), Sci Transl Med, 18
TiO2 Alternative Coatings for Ferric Pyrophosphate Premixes: Stability and Bioaccessibility Relative to Ferrous Fumarate
Journal article
Teichman DL. et al, (2026), Innovative Food Science and Emerging Technologies, 111
TRANSFORM-1 Phase 3 study: Efficacy and safety of navitoclax plus ruxolitinib in patients with untreated myelofibrosis.
Journal article
Pemmaraju N. et al, (2026), Blood
ChatMDV: Reducing Technical Barriers in Bioinformatics Analysis using Large Language Models.
Journal article
Kiourlappou M. et al, (2026), Gigascience
IL-4 peptide hydrogel reprograms MSC heterogeneity toward the CD106+ population for enhanced renal repair.
Journal article
Pan K. et al, (2026), Proc Natl Acad Sci U S A, 123
Development of a recombinant single-cycle influenza viral vector as an intranasal vaccine against SARS-CoV-2.
Journal article
Munro J. et al, (2026), Sci Rep
Multiome-based identification of molecular markers for prospective identification of platelet-biased HSCs.
Journal article
Zhang B. et al, (2026), Stem Cell Reports
Positive allosteric modulator selective for adult muscle nicotinic acetylcholine receptor.
Journal article
Webster RG. et al, (2026), Proc Natl Acad Sci U S A, 123
Transcriptomic analysis of tissue-resident memory T cells of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention
Journal article
AHMED A., (2026), Nature Communications
Transmission ratio distortion of NF1 mutant alleles in familial Neurofibromatosis type 1
Journal article
Pei Y. et al, (2026), Genetics in Medicine
Inhibition of MLLT1 limits growth of KMT2A::AFF1 leukaemias without killing healthy haematopoietic stem cells.
Journal article
Rajhansa S. et al, (2026), Exp Hematol
Nucleophagy removes cytotoxic trapped PARP1.
Journal article
Hoslett G. et al, (2026), Nat Cell Biol
Beyond ATRX: The heterogeneous basis of Alternative Lengthening of Telomeres in osteosarcoma.
Journal article
Goncalves T. et al, (2026), Cancer Genet, 306-307, 123 - 129
Clinical Equipoise and Unimproved Outcomes following Posttransplant Cutaneous Squamous Cell Carcinoma.
Journal article
Crisp THJ. et al, (2026), Kidney Int Rep, 11
Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults-A Pilot Study.
Journal article
Alsaleh G. et al, (2026), Aging Cell, 25
Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago.
Journal article
Macleod R. et al, (2026), Nature, 654, 697 - 705
High Accuracy in Patient Self-Reporting of Keratinocyte Carcinoma, but Reduced Sensitivity for Squamous Cell Carcinoma: A Multicenter Study.
Journal article
Riddle A. et al, (2026), Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
FINE-EM-seq: a rapid isothermal amplification method enabling comprehensive methylome profiling of zebrafish early embryos
Journal article
Ding C. et al, (2026), Cell Insight, 5