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Researchers in the Simmons lab chart the embryonic origins and appearance of diverse intestinal cellular compartments, with important implications for intestinal diseases.
Protecting lactoferrin for iron delivery: Effects of matrix composition and iron loading on gastric stability
Journal article
Blanco-Doval A. et al, (2026), Food Hydrocolloids, 174
The 9th International RASopathies Symposium.
Journal article
Castel P. et al, (2026), Am J Med Genet A
A functional overlap between actively transcribed genes and chromatin insulator elements.
Journal article
Cornell LJ. et al, (2026), EMBO J
Gain and Loss of FLT3 Mutations in Patients with Acute Myeloid Leukemia: A Noninterventional Cohort Study (CLEVO).
Journal article
Papayannidis C. et al, (2026), Oncol Ther
A mechanism to initiate emergency type 2 myelopoiesis.
Journal article
Fagnan A. et al, (2026), Nature
Protocol for stable cell line production to express muscle-type nicotinic receptor.
Journal article
Li A. et al, (2026), STAR Protoc, 7
Expanding the phenotypic spectrum associated with ZIC1 variants: a neurodevelopmental disorder with and without craniosynostosis
Journal article
TWIGG S., (2026), Genetics in Medicine
Single intramuscular injection of self-amplifying RNA of Nppa to treat myocardial infarction.
Journal article
Zhang K. et al, (2026), Science, 391
RLevolution: Unravelling the history of genomic instability through deep reinforcement learning
Journal article
AHMED A., (2026), Royal Society Open Science
Engineering bone-marrow in a dish - a bloody business: Pre-clinical opportunities, translational use-cases, and a call for consensus.
Journal article
North D. et al, (2026), J Thromb Haemost
BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting Drugs.
Journal article
Ng HL. et al, (2026), Adv Sci (Weinh)
Context-specific regulatory genetic variation in MTOR dampens neutrophil-T cell crosstalk in pneumonia-associated sepsis.
Journal article
Zhang P. et al, (2026), Nat Commun
FACT safeguards promoter topology by maintaining nucleosomes and restricting chromatin factor spreading
Preprint
Dopico-Fernandez AM. et al, (2026)
Facilitators may represent a new class of regulatory elements.
Journal article
Kassouf M. et al, (2026), Curr Opin Genet Dev, 97
Integrative multi-omics defines melanoma drug response networks and ARID1A-dependent resistance mechanisms.
Journal article
Barker CG. et al, (2026), Mol Syst Biol
Signalome-wide mapping of the NFκB pathway in T-cells reveals novel targets for immunotherapy
Preprint
Clarke J. et al, (2026)
ATRX loss couples genome instability at a G-rich repeat to dysregulation of human alpha-globin expression.
Journal article
Shen Y. et al, (2026), Nat Commun
High-throughput monoclonal gammopathy community monitoring programme.
Journal article
Agarwal G. et al, (2026), Br J Haematol
PAXIS: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Phase 2 Study (Part 1) Followed by an Open-Label Period (Part 2) to Assess the Efficacy and Safety of Pacritinib in Patients with VEXAS Syndrome.
Journal article
Beck DB. et al, (2026), J Clin Med, 15
Prognostic impact of myelodysplasia-related gene mutations in FLT3-ITD-mutated acute myeloid leukemia.
Journal article
Mecklenbrauck R. et al, (2026), Leukemia