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Haematological studies in a group of Gambian children with severe anaemia due to Plasmodium falciparum malaria revealed marked dyserythropoietic changes in erythroblasts and evidence of increased ineffective erythropoiesis. In some cases, the bone marrow also showed a few giant metamyelocytes and ring sideroblasts. The results of deoxyuridine suppression tests indicated that these haematological disturbances were not a consequence of vitamin B12 or folate deficiency within marrow cells.

More information Original publication

DOI

10.1016/0035-9203(84)90173-1

Type

Journal article

Publication Date

1984-01-01T00:00:00+00:00

Volume

78

Pages

60 - 63

Total pages

3

Keywords

Anemia, Bone Marrow, Child, Preschool, DNA, Deoxyuridine, Erythropoiesis, Folic Acid, Humans, Infant, Malaria, Plasmodium falciparum, Vitamin B 12