Of Dots and Stripes: The Morse Code of Micro-C Reveals the Ultrastructure of Transcriptional and Architectural Mammalian 3D Genome Organization.

Chang L-H., Noordermeer D.

Using Micro-C, Hsieh et al. (2020) and Krietenstein et al. (2020) investigated 3D chromatin folding in human and mouse cells at unprecedented resolution to uncover ultra-fine-scale chromatin structures that provide direct links between genome architecture, gene expression, and gene regulation.

DOI

10.1016/j.molcel.2020.04.021

Type

Journal article

Publication Date

2020-05-07T00:00:00+00:00

Volume

78

Pages

376 - 378

Total pages

2

Keywords

Animals, Chromatin, Gene Expression Regulation, Genome, Humans, Mammals, Mice

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