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The random association of Epstein-Barr virus DNA with host cell metaphase chromosomes of all sizes in Burkitt's lymphoma-derived cell lines was demonstrated by two substantially different techniques, namely fluorescence-activated chromosome sorting and in situ hybridization. The nature and potential importance of this association are discussed.

Type

Journal article

Journal

J Virol

Publication Date

10/1985

Volume

56

Pages

328 - 332

Keywords

Burkitt Lymphoma, Cell Line, Cell Transformation, Viral, Chromosome Mapping, DNA, Viral, Extrachromosomal Inheritance, Genetic Linkage, Herpesvirus 4, Human, Humans, Karyotyping, Metaphase, Nucleic Acid Hybridization, Plasmids