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Physical inactivity accelerates bone loss. Since patients with fibromyalgia are relatively physically inactive, bone mass and markers of bone metabolism were determined in 12 premenopausal women with fibromyalgia and in healthy age matched female control subjects. No differences were found in lumbar bone mineral density, femoral neck bone mineral density, serum levels of alkaline phosphatase, osteocalcin, ionized calcium and phosphate. The urinary excretion of both hydroxyproline and calcium relative to urinary creatinine excretion was significantly higher in patients with fibromyalgia, p = 0.01. This was linked to lower urinary creatinine excretion (p = 0.02) probably reflecting lower physical activity in the patients with fibromyalgia. We conclude that bone mass and turnover are generally not affected in premenopausal women with fibromyalgia.

Type

Journal article

Journal

J Rheumatol

Publication Date

05/1993

Volume

20

Pages

856 - 859

Keywords

Absorptiometry, Photon, Adult, Biomarkers, Bone Density, Bone Resorption, Bone and Bones, Female, Fibromyalgia, Humans, Middle Aged, Osteogenesis