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Research into two of the four classes of naturally produced beta-lactams--the clavams and carbapenems--has started to throw light upon their biochemical pathways and underlying genetics. Interesting similarities between these two classes, from their joint discovery to an apparently common beta-lactam ring-forming enzyme, are now being revealed.

Original publication

DOI

10.1016/s0966-842x(98)01251-7

Type

Journal article

Journal

Trends Microbiol

Publication Date

05/1998

Volume

6

Pages

203 - 208

Keywords

Anti-Bacterial Agents, Carbapenems, Clavulanic Acids, beta-Lactams