Imaging vasculature and lymphatic flow in mice using quantum dots.
Ballou B., Ernst LA., Andreko S., Fitzpatrick JAJ., Lagerholm BC., Waggoner AS., Bruchez MP.
Quantum dots are ideal probes for fluorescent imaging of vascular and lymphatic tissues. On injection into appropriate sites, red- and near-infrared-emitting quantum dots provide excellent definition of vasculature, lymphoid organs, and lymph nodes draining both normal tissues and tumors. We detail methods for use with commercially available quantum dots and discuss common difficulties.