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In this issue of Cancer Cell, Wong and colleagues describe a novel approach of increasing the number of functional blood vessels in tumors using a low-dose therapy regimen of Cilengtide and Verapamil. This method enhanced gemcitabine delivery, uptake, and metabolism within tumor cells to reduce tumor growth and progression.

Original publication

DOI

10.1016/j.ccell.2014.12.009

Type

Journal article

Journal

Cancer cell

Publication Date

12/01/2015

Volume

27

Pages

7 - 9

Keywords

Animals, Antimetabolites, Antineoplastic, Carcinoma, Lewis Lung, Deoxycytidine, Humans, Pancreatic Neoplasms, Snake Venoms, Verapamil