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It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT-PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. We aimed to detect cell-free mammaglobin mRNA in the plasma of breast cancer patients and to investigate whether it can be used as a marker for diagnosis of breast cancer.

Type

Journal article

Journal

Ann N Y Acad Sci

Publication Date

09/2001

Volume

945

Pages

192 - 194

Keywords

Biomarkers, Tumor, Breast Neoplasms, Female, Humans, Male, Mammaglobin A, Neoplasm Proteins, RNA, Messenger, RNA, Neoplasm, Uteroglobin