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Marieke Oudelaar

PhD


Junior Research Fellow

My research focuses on the mechanisms by which the regulatory elements of the genome control tissue-specific gene expression patterns. In particular, I am interested in the relationship between the structural, three-dimensional organisation of the genome in the nucleus and the regulation of gene expression. My main goals are to understand how regulatory elements interact within nuclear chromatin structures, when and how such structures are established during development, and how disruptions of these structures cause mis-regulation of gene expression and contribute to human disease.

Key publications

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