Natalia Sampaio

BSc (Hons); PhD

Postdoctoral Scientist

Natalia Sampaio obtained a Bachelor of Science in Molecular Biotechnology (Curtin University, Perth 2007) and Honours in Pharmacology (University of Western Australia 2008). She obtained her PhD from the University of Melbourne and the Walter and Eliza Hall Institute in 2016. There, she investigated virulence and immunomodulatory factors of the malaria parasite, Plasmodium falciparum. Natalia's interests are in innate immunity to pathogens and host-pathogen interactions. She is currently investigating the pathogen recognition receptor MDA5, and how it detects viral infections.

Recent publications

A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation.
Journal article

Dias Junior AG. et al, (2019), Trends Microbiol, 27, 75 - 85
Extracellular vesicles from early stage Plasmodium falciparum-infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes.
Journal article

Sampaio NG. et al, (2018), Cell Microbiol, 20
Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression.
Journal article

Sampaio NG. et al, (2018), PLoS One, 13
Plasmodium falciparum PfEMP1 Modulates Monocyte/Macrophage Transcription Factor Activation and Cytokine and Chemokine Responses.
Journal article

Sampaio NG. et al, (2018), Infect Immun, 86
Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors.
Journal article

Sisquella X. et al, (2017), Nat Commun, 8

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