MA (Oxon), MD, FMedSci, FRCPCH, FMH Paediatrics (CH)
Hoffmann and Action Medical Research Professor of Developmental Medicine
- Head of Department
Understanding the development and function of the immune system in health and disease
Prof. Georg A Holländer was trained in both Paediatrics and Experimental Immunology in Switzerland and the U.S. He held academic positions at Harvard Medical School, Boston, U.S. and the University of Basel, Switzerland, before he joined the University of Oxford, UK (2010). He is interested in the development and function of the immune system in health and disease. His particular scientific focus concerns the molecular and cellular control of thymus development and function.
The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity.
Newman JA. et al, (2019), J Biol Chem
Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells".
Handel AE. and Holländer GA., (2019), Journal of immunology (Baltimore, Md. : 1950), 203
Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells.
Dhalla F. et al, (2019), The EMBO journal
Florescent timer protein as a molecular stop watch during embryonic thymic epithelial cell development
Cheuk S. et al, (2019), EUROPEAN JOURNAL OF IMMUNOLOGY, 49, 355 - 356
Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches.
Bortolomai I. et al, (2019), Stem Cells Transl Med