MA (Oxon), MD, FMedSci, FRCPCH, FMH Paediatrics (CH)
Hoffmann and Action Medical Research Professor of Developmental Medicine
- Head of Department
Understanding the development and function of the immune system in health and disease
Prof. Georg A Holländer was trained in both Paediatrics and Experimental Immunology in Switzerland and the U.S. He held academic positions at Harvard Medical School, Boston, U.S. and the University of Basel, Switzerland, before he joined the University of Oxford, UK (2010). He is interested in the development and function of the immune system in health and disease. His particular scientific focus concerns the molecular and cellular control of thymus development and function.
RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.
Paolino M. et al, (2020), Nature
Ageing compromises mouse thymus function and remodels epithelial cell differentiation.
Baran-Gale J. et al, (2020), Elife, 9
Ageing compromises mouse thymus function and remodels epithelial cell differentiation
HOLLANDER G. et al, (2020), eLife
The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity.
Newman JA. et al, (2020), J Biol Chem, 295, 2948 - 2958
Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells.
Dhalla F. et al, (2020), EMBO J, 39