MA (Oxon), MD, FMedSci, FRCPCH, FMH Paediatrics (CH)
Hoffmann and Action Medical Research Professor of Developmental Medicine
- Head of Department
Understanding the development and function of the immune system in health and disease
Prof. Georg A Holländer was trained in both Paediatrics and Experimental Immunology in Switzerland and the U.S. He held academic positions at Harvard Medical School, Boston, U.S. and the University of Basel, Switzerland, before he joined the University of Oxford, UK (2010). He is interested in the development and function of the immune system in health and disease. His particular scientific focus concerns the molecular and cellular control of thymus development and function.
Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches.
Bortolomai I. et al, (2019), Stem Cells Transl Med
Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity.
Jayachandran R. et al, (2019), Immunity, 50, 152 - 165.e8
Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho.
Xing Y. et al, (2018), J Immunol, 201, 3320 - 3328
The role of thymic tolerance in CNS autoimmune disease.
Handel AE. et al, (2018), Nat Rev Neurol, 14, 723 - 734
Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis
Gai H. et al, (2018), BLOOD, 132