My research projects aim at a thorough understanding of the role of heterogeneity in molecular membrane organization on the functionality of the membrane-related immunological signalling events.
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.
Rota IA. et al, (2021), Sci Adv, 7
Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes
Carravilla P. et al, (2021), Biophysical Reports, 1, 100023 - 100023
The influence of the extracellular domains on the dynamic behavior of membrane proteins
Wedemann L. et al, (2021)
Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.
Matias MI. et al, (2021), Cell Rep, 37
Aggregation and partial immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells.
Urbančič I. et al, (2021), FEBS Lett