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Contact information
DPhil research opportunity
Edward Morrissey
MRC WIMM Group Leader
I received my MPhys in Theoretical Physics from the Universidad Autonoma de Madrid in Spain. Prior to starting my PhD I worked as a consultant in industry and held several research positions working on Nuclear Physics (Spanish National Research Council), Theoretical Neuroscience (Theoretical Physics Department UAM) and Computational Biology (Spanish National Cancer Research Centre). I completed my PhD in Warwick University’s Systems Biology DTC where I worked on developing Bayesian methods to study large gene regulatory networks. After my PhD I moved to Cambridge where I was a Postdoctoral Fellow in Prof Simon Tavaré’s group at CRUK/Cambridge University. During my stay in Cambridge I developed an interest in cellular fate choices in mammalian tissues. Specifically, while in Cambridge, I developed mathematical models of stem cells in order to understand their stochastic behaviour and how this behaviour was altered by oncogenic mutations.
In November 2016 I moved to the Weatherall Institute to set up a Quantitative Biology group. The groups focus is to study cell fate choices, applying techniques such as Stochastic Modelling, Bayesian Inference and Deep Learning.
Recent publications
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Spatiotemporal analysis of human intestinal development at single-cell resolution.
Journal article
Fawkner-Corbett D. et al, (2021), Cell
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Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing.
Journal article
Thorsen A-S. et al, (2020), Dis Model Mech
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Single-cell fate decisions of bipotential hematopoietic progenitors.
Journal article
Brand M. and Morrissey E., (2020), Curr Opin Hematol, 27, 232 - 240
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Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing
Journal article
Thorsen A-S. et al, (2020)
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An Assessment of the Mutation Rate or Normal Colorectal Epithelium in Patients with Cancer Compared to Patients Without
Conference paper
Marks KM. et al, (2019), JOURNAL OF PATHOLOGY, 249, S38 - S38