Research groups
Damien Downes
BSc (Hons), PhD
Postdoctoral Researcher
Key publications
-
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.
Journal article
Oudelaar AM. et al, (2018), Nat Genet, 50, 1744 - 1751
-
Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.
Journal article
Hanssen LLP. et al, (2017), Nat Cell Biol, 19, 952 - 961
Recent publications
-
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale.
Journal article
Downes DJ. et al, (2021), Nat Commun, 12
-
Recapitulation of erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities.
Journal article
Scott C. et al, (2020), Haematologica, Online ahead of print
-
Genetic and functional insights into CDA-I prevalence and pathogenesis.
Journal article
Olijnik A-A. et al, (2020), J Med Genet
-
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.
Journal article
Godfrey L. et al, (2019), Nat Commun, 10