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Researchers from the MRC-Human Immunology Unit, supported by the NIHR Oxford Biomedical Research Centre, have used an ‘atlas’ of immune cells in the human colon to find evidence of the role of CD8 T cells in inflammatory bowel disease. The findings could pave the way for more targeted treatments for this chronic disorder.
Koohy Group: Machine Learning and Integrative Approaches in Immunology
Centre for Computational Biology MRC TIDU
We would like to understand the functional and molecular mechanisms of the immune system in various immunologically important conditions such as cancer, infection, autoimmune disease as well as ageing. We have a special interest in computational cancer immunotherapy such as antigen presentation, neo-antigen identification and T cell recognition of neo-antigens as well as interrogating the immune response to personalized vaccines from neo-antigens.
Sahakyan Group: Integrative Computational Biology and Machine Learning
Centre for Computational Biology
Combining computational biology, computational chemistry, and machine learning techniques with biological big data to unravel the higher genomic code of life.
Sims Group: Computational Genomics
Centre for Computational Biology
We are a computational biology research group using genomic and functional genomic data to study transcriptional regulation in neuroscience.
Hughes Group: Genome Biology
Centre for Computational Biology MRC MHU
Using genomics, computational and synthetic biology approaches to understand how genes are regulated in health and disease.