The Fourth International Symposium on Genetic Disorders of the Ras/MAPK pathway.
Stevenson DA., Schill L., Schoyer L., Andresen BS., Bakker A., Bayrak-Toydemir P., Burkitt-Wright E., Chatfield K., Elefteriou F., Elgersma Y., Fisher MJ., Franz D., Gelb BD., Goriely A., Gripp KW., Hardan AY., Keppler-Noreuil KM., Kerr B., Korf B., Leoni C., McCormick F., Plotkin SR., Rauen KA., Reilly K., Roberts A., Sandler A., Siegel D., Walsh K., Widemann BC.
The RASopathies are a group of disorders due to variations of genes associated with the Ras/MAPK pathway. Some of the RASopathies include neurofibromatosis type 1 (NF1), Noonan syndrome, Noonan syndrome with multiple lentigines, cardiofaciocutaneous (CFC) syndrome, Costello syndrome, Legius syndrome, and capillary malformation-arteriovenous malformation (CM-AVM) syndrome. In combination, the RASopathies are a frequent group of genetic disorders. This report summarizes the proceedings of the 4th International Symposium on Genetic Disorders of the Ras/MAPK pathway and highlights gaps in the field. © 2016 Wiley Periodicals, Inc.