Single Cell Whole Genome Amplification

A variety of single cell and small sample methodologies have been reported for genomic DNA amplification. These include multiple displacement amplification (MDA), MALBAC and various commercial kits.

MDA
Multiple Displacement Amplification

We currently offer an in house Phi29 multiple displacement amplification assay as a low cost method for amplification but we can use any commercial kit according to need. For human samples we can also offer a multiplex chromosome PCR analysis to help check amplification bias, and select the best samples to sequence. Please contact the Facility Manager to discuss your project.