Occasional WIMM Seminars

Fri 14 Oct 2016 from 13:00 to 14:00

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Nuclear inositide pathways: Phospholipase C signalling and initiation of cancer

Professor Lucio Cocco

Audience: Members of the University only

Organisers: Liz Rose

Thu 20 Oct 2016 from 12:30 to 13:30

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Decoding the human antiviral gene expression code

Dr Marios Agelopoulos

Viral-Infections cause dramatic changes in gene expression by mobilizing defined sets of transcriptional regulatory proteins. We speculate that Virus-Infection reprograms the human genome by inducing global transcriptional changes and alterations in chromatin structure. We aim to understand at the... Read more

Viral-Infections cause dramatic changes in gene expression by mobilizing defined sets of transcriptional regulatory proteins. We speculate that Virus-Infection reprograms the human genome by inducing global transcriptional changes and alterations in chromatin structure. We aim to understand at the molecular level the mechanisms by which human cells reconfigure their genome in order to respond accurately to Viral-Infection signal(s) by applying genomics in naïve and infected human cell lines. Thus, we perform an holistic genome-wide study in distinct human cell lines to decode the molecular logic/mechanism that cells employ to switch on or off the appropriate battery of genes required for an efficient antiviral response.

Audience: Members of the University only

Organisers: Penny Berry

Tue 25 Oct 2016 from 12:00 to 12:30

MRC Weatherall Institute of Molecular Medicine, Seminar room, Headington OX3 9DS

Molecular mechanisms regulating human pluripotent stem cell differentiation

Dr Siim Pauklin

Audience: Members of the University only

Organisers: Liz Rose