Current publications 

Guillard, S., Kolasinska-Zwierz, P., Debreczeni, J., Breed, J., Zhang J, Bery, N, Marwood R., Tart, Overman, R., Stocki, P., Mistry, B., Phillips, C., Rabbitts, T., Jackson, R., Minter, R. (2017) Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange. Nature Communications 8, 16111
https://www.ncbi.nlm.nih.gov/pubmed/28706291

 

Bao, L,. Al-Assar, O., Drynan, L.F., Arends, M.J., Tyers, P., Barker, R.A., Rabbitts, T.H. (2017) A non-cell autonomous mouse model of CNS haemangioblastoma mediated by mutant KRAS. Scientific Reports 7, 44899
https://www.ncbi.nlm.nih.gov/pubmed/28322325

 

Ruggero, K., Al-Assar, O., Chambers, J.C., Codrington, R., Brend, T., Rabbitts, T.H. (2016) LMO2 and IL2RG synergize in thymocytes 5 to mimic the evolution of SCID-X1 gene therapy-associated T cell leukaemia. Leukemia 30, 1959-1962
http://www.ncbi.nlm.nih.gov/pubmed/27256700

 

Town, J., Pais, H., Harrison, S., Stead, L.F., Bataille, C., Bunjobpol, W., Zhang, J., Rabbitts, T.H. (2016) Exploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic target. Proc. Natl. Acad. Sci. USA 113, 3603-3608
http://www.ncbi.nlm.nih.gov/pubmed/26979953

 

Zeng, J., Li, H.C., Tanaka, T., Rabbitts, T.H. (2015)  Selection of human single domain antibodies recognizing the CMYC protein using enhanced intracellular antibody capture. J Immunol Methods
http://www.ncbi.nlm.nih.gov/pubmed/26319394

 

Chambers, J., Rabbitts, T.H. (2015) LMO2 at 25 years: a paradigm of chromosomal translocation proteins. Open Biol 5
http://www.ncbi.nlm.nih.gov/pubmed/26108219

 

Zhang, J. & Rabbitts, T.H.  (2014)  Intracellular Antibody Capture:  a molecular biology approach to inhibitors of protein-protein interactions; BBA – Proteins and Proteomics 1844, 1970 - 1976
http://www.ncbi.nlm.nih.gov/pubmed/24881582

 

Newnham, L.E., Wright, M.J., Holdsworth, G., Kostarelos, K., Robinson, M.R., Rabbitts, T.H. & Lawson, A.D. (2015)  Functional inhibition of Beta-catenin-mediated Wnt signalling by intracellular VHH antibodies.  mAbs  7:1, 1-12, January/February 2015
http://www.ncbi.nlm.nih.gov/pubmed/25524068

 

Peirs, S., Matthijssens, F., Goossens, S., Van de Walle, I., Ruggero, K., de Brock, C.E., Degryse, S., Cante-Barrett, K., Briot, D., Clappier, E., Lammens, T., De Moerloose, B., Benoit, Y., Poppe, B., Meijerink, J., Cools, J., Soulier, J., Rabbitts, T. H., Taghon, T., Speleman, F. & Van Vlierberghe, P.  (2014)  ABT-199 Mediated Inhibtion of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.  Blood Dec;124(25):3738-47
http://www.ncbi.nlm.nh.gov/pubmed/25301704

 

Chambers, J.S., Tanaka, T., Brend, T., Ali, H., Geisler, N.J., Khazin. L., Cigudosa, J.C., Dear, T.N., MacLennan, K. & Rabbitts, T.H. (2014) Sequential gene targeting to make chimeric tumor models with de novo chromosomal abnormalities; Cancer Res 74, 1588-1597   http://www.ncbi.nlm.nih.gov/pubmed/24419086

 

Sewell, H., Tanaka, T., El Omari, K., Mancini, E.J., Cruz, A., Fuentes-Fernandez, N., Chambers, J. & Rabbitts T.H. (2014) Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcriptional complex; Scientific Reports 4, 1-9     http://www.ncbi.nlm.nih.gov/pubmed/24407558

 

El-Jawhari, J.J., El-Sherbiny, Y.M., Scott, G.B., Morgan, R.S., Prestwich, R., Bowles, P.A., Blair, G.E., Tanaka, T., Rabbitts, T.H., Meade, J.L., & Cook, G.P. (2014) Blocking oncogenic RAS enhances tumour cell surface MHC class 1 expression but does not alter susceptibility to cytotoxic lymphocytes; Mol. Immunol. 58, 160-168      
http://www.ncbi.nlm.nih.gov/pubmed/24365750

 

McCormack, M.P., Shields, B.J., Jackson, J.T., Nasa, C., Shi, W., Slater, N.J., Tremblay, C.S., Rabbitts, T.H. & Curtis, D.J. (2013) Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL; Blood 122, 2093-2103       
http://www.ncbi.nlm.nih.gov/pubmed/23926305

 

Li, B.E., Gan, T., Meyerson, M., Rabbitts, T.H. & Ernst, P. (2013) Distinct Pathways Regulated by Menin and by MLL1 in Hematopoietic Stem Cells and Developing B-cells; Blood 122, 2039-2046 http://www.ncbi.nlm.nih.gov/pubmed/23908472

 

Cruz-Mignoni, A., Fuentes-Fernandez, N. & Rabbitts, T.H. (2013) Peptides: minimal drug surrogates to interrogate and interfere with protein function; MedChemComm 4, 1218-1221    http://pubs.rsc.org/en/content/articlelanding/2013/md/c3md00142c#!divAbstract

 

Zeng, J., Zhang, J., Tanaka, T. & Rabbitts, T.H. (2013) Single Domain Antibody Fragments as Drug Surrogates Targeting Protein-Protein Interactions inside Cells; Antibodies 2, 306-320,    http://www.mdpi.com/2073-4468/2/2/306

 

Ali, H., Daser, A., Dear, P.H., Wood, H.M., Rabbitts, P.H. & Rabbitts, T.H. (2013) Non-reciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription; Genes, Chromosomes and Cancer 52, 402-409,  
http://www.ncbi.nlm.nih.gov/pubmed/23341332